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COVID-19 Reopening Updates View Update Virtual Consultation

breast implants and lymphomaIn a recent publication, the FDA indicated a small risk between breast implants and a rare form of blood cancer. The type of cancer is called anaplastic large cell lymphoma (ALCL), a form of non-Hodgkins lymphoma, a cancer of the T-cell lymphocytes cells in the blood.

The most important aspect of this recent FDA announcement is the personal risk to each patient who has undergone a breast augmentation.  Fortunately, the risk is minimal.  Only 50 cases have been reported (some may be duplicates) in the estimated 5-10 million breast augmentations that have been employed worldwide. That puts an individual’s risk at 0.0012-0.0006 percent.  Keep in mind that 1 in every seven women will be diagnosed with breast cancer alone.  That is a 14% chance that can be as high as 50% in certain women with higher genetic risk factors or positive family history.

This relationship has been seen with both implant textures, smooth and textured, but more commonly in the textured type.  Fortunately, this type is no longer on the US market and had been infrequently used in the United States.  Most implants in the US are smooth, round saline or silicone implants.

No real association has been established between breast implants and lymphoma through multiple studies.

The potential association of breast implants and lymphoma has been evaluated in several studies with long term follow up, and the published epidemiological evidence does not support an increased risk of non-Hodgkin’s lymphoma in patients with breast implants:

  • An epidemiological study reviewed evidence from five long-term studies of 43,000 women with breast implants and followed for up to 37 years and noted no difference in non-Hodgkin’s lymphoma incidence in implant patients (Lipworth, March 2009).
  • A Scandinavian cancer incidence study evaluated 6,222 women with breast implants, including 3,336 women with 15 or more years of follow-up and 827 with 25 or more years of follow-up, and found no excess of lymphoma in subjects with implants (Lipworth, Jan 2009).
  • A large, controlled Canadian cancer study followed 24,558 breast augmentation patients and 15,893 women who received other cosmetic surgeries and found a similar incidence of non-Hodgkin’s lymphoma after over 600,000 person-years of follow-up (Brisson, 2006).
  • A Dutch study concluded there might be an association of ALCL and breast implants but suffered methodologically (Evens 2008) by having controls that were not comparable to the cases (ALCL) since the controls were lymphomas other than ALCL (de Jong, 2008). They reported that 6 of 11 primary breast ALK1-negative ALCLs had no history of silicone breast implantation, while five did, and one patient developed ALCL one year after cosmetic implantation. The author’s analysis was also based on five saline-filled breast implants—including two initially observed or “trigger” cases of women with both ALCL and breast implants over 17 years.
  • The results of the Allergan Breast implant sponsored clinical trials have been reported at the ASPS meeting in Toronto (October 2010). For all 89,382 patients, with 204,681 patient-years of follow-up, the number of lymphomas observed divided by those expected (26/43) yields a standardized incidence ratio (SIR) of 0.6.

Several studies have shown that women with breast implants have an overall lower risk of breast cancer than the general population. (Deapen DM, 1997 & 2007)   ALCL comprises a tiny percentage of all lymphomas and is an infrequent pathological entity (0.2 per 100,000 person-years) (SEER 2008).

With the infrequent incidence of ACLC, there is limited ability to make any formal conclusions relating to lymphoma and breast implants. Active, ongoing research is underway to understand the relationships relating to breast implants and lymphoma development, but little evidence currently suggests any causal relationship.

Some of the unlikely events that might happen in one’s life that are MORE likely than getting ALCL cancer relating to breast implants are:

0.054% – the chance of dying from a car accident

0.0012 % – the chance of dying from an accidental drowning

0.0012 % – the chance of dying from a fire or smoke inhalation

0.0012-0.0006% – ALCL from breast implants

12.2% – the chance of breast cancer with or without implants (1 in 8 women)

The possibility of breast cancer appears to be 10,000 times more likely with the current information we presently have available.

In conclusion, although it has come to light that there have been several patients who developed ALCL in the setting of having a previous breast augmentation, no causal or linked relationship has been demonstrated.  The risks are extremely low and are not currently connected to the presence of breast implants.  Both the American Society of Plastic Surgeons and the American Society for Aesthetic Plastic Surgery has not recommended a change in current practice or how breast augmentation procedures are performed.

*The content in this blog is developed to spread the awareness towards plastic surgery. Our blog is not intended to serve as a replacement for an actual in-office consultation with Dr. Marin. As such, the information within this blog reflects the unique cases of our individual patients.

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In light of the state wide restrictions on non-essential businesses to help reduce the spread of COVID-19, we are rescheduling all of our elective appointments until the global circumstances improve. Our necessary post-operative appointments will be made, as needed, to address immediate surgical concerns such as suture removal and acute postoperative issues. All non-acute follow up appointments, fillers and Botox will need to be postponed until after the quarantine period mid April. Our office will reach out to all patients who need to be rescheduled.

We will be offering new patient virtual consultations online and via Skype that can be scheduled through our website or by emailing Also, we will offer follow-up appointments in the same manner to help manage our patients’ concerns while still respecting the need for social distancing.

We appreciate all of your understanding during these difficult times for all of us.

Stay safe,

Dr. Main and the Marin Aesthetics Team